Mouse Monoclonal Antibody to CD206
Catalog No.:FA02139 【Specification】
Aliases : MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1
Entrez GeneID :
4360
Swissprot :
P22897
clone :
1E12A7
WB Predicted band size :
166 kDa
Host/Isotype :
Mouse IgG1
Antibody Type:
Primary antibody
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity:
Human,Mouse,Rat
Immunogen :
Purified recombinant fragment of human CD206 (AA: extra(19-218))expressed in E. Coli.
Formulation:
Purified antibody in PBS with 0.05% sodium azide
【Description】
The recognition of complex carbohydrate structures on glycoproteins is animportant part of several biological processes, including cell-cell recognition, serumglycoprotein turnover, and neutralization of pathogens. The protein encoded by thisgene is a type I membrane receptor that mediates the endocytosis of glycoproteinsby macrophages. The protein has been shown to bind high-mannose structures onthe surface of potentially pathogenic viruses, bacteria, and fungi so that they can beneutralized by phagocytic engulfment.
【Application】
IF
1/200 - 1/ 1000
FCM
1/200 - 1/400
For Research Only-Time Saved, Science Advanced苏州丰度蛋白生物技术有限公司(www.fedprotein.com)
Immunofluorescence analysis of Hela cells
using CD206 mouse mAb (green). Blue:
DRAQ5 fluorescent DNA dye. Red: Actin
filaments have been labeled with Alexa Fluor-
555 phalloidin. Secondary antibody from Fisher
Flow cytometric analysis of MOLT4 cells using
CD206 mouse mAb (green) and negative
control (red).
Flow cytometric analysis of U937 cells using
CD206 mouse mAb (green) and negative
control (red).